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Physical activity and quality of life in multiple sclerosis: intermediary roles of disability, fatigue, mood, pain, self-efficacy and social support.

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Medical Update Memo
January 8, 2009

Summary

Researchers at the University of Illinois report on studies supporting that physical activity is associated with a small improvement in quality of life (QOL) among those with multiple sclerosis (MS). This relationship may be indirect and operate through factors such as disability, fatigue, mood, pain, self-efficacy and social support. Psychol Health Med. 2009 Jan;14(1):111-24

Details

The present study examined variables that might account for the relationship between physical activity and quality of life (QOL) in a sample (N = 292) of individuals with a definite diagnosis of MS. The participants wore an accelerometer for 7 days and then completed self-report measures of physical activity, QOL, disability, fatigue, mood, pain, self-efficacy and social support.

Those who were more physically active reported lower levels of disability, depression, fatigue and pain. Physically active study participants also reported higher levels of social support, self-efficacy for managing MS , and self-efficacy for regular physical activity . In turn, those who reported lower levels of depression , anxiety , fatigue and pain and higher levels of social support and self-efficacy for controlling MS  reported higher levels of QOL. The observed pattern of relationships supports the possibility that physical activity is indirectly associated with improved QOL in individuals with MS via depression, fatigue, pain, social support and self-efficacy for managing MS.

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The Multiple Sclerosis Society of Canada is an independent, voluntary health agency and does not approve, endorse or recommend any specific product or therapy, but provides information to assist individuals in making their own decisions.

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